Reduced pubertal growth in children with obesity regardless of pubertal timing

DOHAD and early pubertal timing

Age at menarche varies widely between girls, is estimated to be highly heritable and is associated with long-term health outcomes, such as obesity and type 2 diabetes. Earlier pubertal maturation in boys and girls links rapid postnatal growth weight gain to later life metabolic and cardiovascular disease [1,2]. Genome-wide association studies (GWAS), which genotype hundreds of thousands of comm...

Pubertal growth in diabetics.

Mean values for two variables of the pubertal growth spurt, peak height velocity and age at peak velocity, of children attending the diabetic clinic in Bristol are reported. The growth spurt was normal both in timing and intensity in boys, but the peak velocity was reduced and age at peak velocity more variable among girls.

Forty Years Trends in Timing of Pubertal Growth Spurt in 157,000 Danish School Children

BACKGROUND Entering puberty is an important milestone in reproductive life and secular changes in the timing of puberty may be an important indicator of the general reproductive health in a population. Too early puberty is associated with several psychosocial and health problems. The aim of our study was to determine if the age at onset of pubertal growth spurt (OGS) and at peak height velocity...

Childhood Obesity and Pubertal Development

During the past decades, advancement in pubertal maturation in children has been noticed worldwide. Growing evidence indicates that increasing prevalence of obesity in children is a major factor for the secular trend of earlier puberty. In girls, several epidemiologic studies suggest that earlier pubertal onset and earlier menarche might be caused by obesity. On the other hand, in boys, few res...

Pubertal timing and psychopathology 1 Pubertal Timing and Psychopathology Xiaojia Ge and Misaki N. Natsuaki In Search of Explanations for Early Pubertal Timing Effects on Developmental Psychopathology